Not even among dentists are the names Dr. Joseph Muhler and Dr. William Nebergall well known ( if know at all!). Yet both have just been inducted into the Dental Hall of fame for developing and patenting fluoridated toothpaste in 1950. By 1955 Procter and Gamble launched Crest, the first clinically proven fluoridated toothpaste. The world has seen a tremendous reduction in caries, the disease of dental decay, thanks to Drs. Muhler and Nebergall.